Asian Journal of Immunology https://www.journalaji.com/index.php/AJI <p style="text-align: justify;"><strong>Asian Journal of&nbsp;Immunology</strong>&nbsp;aims to publish&nbsp;high-quality&nbsp;papers (<a href="/index.php/AJI/general-guideline-for-authors">Click here for Types of paper</a>) in all aspects of the immune system in all organisms. This journal facilitates the research and wishes to publish papers as long as they are technically correct, scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer-reviewed, open access INTERNATIONAL journal.</p> <p style="text-align: justify;">&nbsp;</p> en-US contact@journalaji.com (Asian Journal of Immunology) contact@journalaji.com (Asian Journal of Immunology) Sat, 17 Oct 2020 11:08:43 +0000 OJS 3.1.1.4 http://blogs.law.harvard.edu/tech/rss 60 Prevalence of Hepatitis B Virus among Women of Child-Bearing Age in Port Harcourt, Nigeria https://www.journalaji.com/index.php/AJI/article/view/30140 <p><strong>Aim:</strong> Hepatitis B virus among women of child bearing age is a major determinant of perinatal hepatitis B transmission. The risk of developing liver-related complications, such as cirrhosis and hepatocellular carcinomas increases as patient progresses from acute to chronic stage of the infection. The aim of this study was to determine the prevalence of HBV among women of child bearing age in Port Harcourt, Nigeria.</p> <p><strong>Study Design:</strong>&nbsp; Cross-sectional study.</p> <p><strong>Place and Duration of Study:</strong> University of Port Harcourt, Nigeria, between June 2012 and July 2015.</p> <p><strong>Methods: </strong>A total of 89 women of child bearing age in Port Harcourt, Nigeria (ages 15-45 years) were screened for the presence of HBsAg. The presence of HBV was determined using third-generation enzyme linked immunosorbent assay (ELISA) (Bio-Rad, France).</p> <p><strong>Results: </strong>The results showed an overall HBsAg prevalence of 12.4%. Married women (14.3%) were found to be more infected with the highest prevalence rate recorded among the non-students (14.6%) and those within the 25-45 years age group (14%).</p> <p><strong>Conclusion: </strong>This study has shown that the prevalence of HBV among women of child-bearing age is high. Health education on the possible mode of transmission and the introduction of routine screening of women in health facilities will grossly help in reducing the rate of infection.</p> Iheanyi O. Okonko, Onyekachi L. Udo, Tochi I. Cookey, Chisom C. Adim ##submission.copyrightStatement## https://www.journalaji.com/index.php/AJI/article/view/30140 Sat, 17 Oct 2020 00:00:00 +0000 Association between Secretor Status of ABH Substances and HIV 1& 2 P24 Antigen Screening Status Amongst Eligible Blood Donors with Previously Screened HIV 1& 2 Antibody- Negative Status in Calabar, Nigeria https://www.journalaji.com/index.php/AJI/article/view/30142 <p><strong>Aims</strong>: New hypotheses suggest non-secretors may be less vulnerable to the HIV infection than secretors.&nbsp; Association between secretor status and HIV P24 antigen status was studied in 400 HIV antibody sero-negative&nbsp;&nbsp; prospective blood donors aged above 20 years of both genders recruited within Calabar, Nigeria.</p> <p><strong>Materials and Methods:</strong> About&nbsp; 3 ml of saliva and 5ml of blood samples&nbsp; were&nbsp; analyzed&nbsp; for HIV&nbsp; antibodies&nbsp; using Stat Pak (by Chembio Diagnostic System International), Determine (by Inverness Medical Japan Cooperation, Limited), Unigold (by Trinity Biotech, USA) rapid test Kits&nbsp; and&nbsp; antigens&nbsp; using HIV P24 antigens Combi test Kits (by Inverness Medical Japan Cooperation, Limited) respectively.&nbsp; Secretor Status done using Anti-H Lectin reagent by BIOTEC Laboratories Limited, UK.</p> <p><strong>Results:</strong> Out of 400 samples, 80 (20%) were non-secretors and 320(80%) secretors. while 6(8.1%) non-secretor&nbsp; and 9(2.9%) secretor samples&nbsp; reacted to&nbsp; HIV P24&nbsp; antigen screening test. Chi-Square (X<sup>2</sup>=5.655, <em>P</em>=0.025) showed significant difference between secretor and non-secretors based on&nbsp;&nbsp; gender. No significant difference exits between HIV p24 antigen status and secretor status (chi squared X<sup>2</sup> =0.007, <em>P</em> =0.9) and&nbsp;&nbsp; secretor status and the three HIV Antibody test kits (F -ratio = 1.7997, <em>P</em> =0.307)</p> <p><strong>Conclusion:</strong> No significant association found between secretor status and HIV P24 antigen status but detectable P24 antigens were more in secretors than non-secretos.</p> Forwah Jacques Ndeh, Ebot Walter Ojong, Immaculate Ihuoma Ekeagba ##submission.copyrightStatement## https://www.journalaji.com/index.php/AJI/article/view/30142 Mon, 30 Nov 2020 00:00:00 +0000 Prevention, Possible Treatment and Control of Corona Virus (SARS-CoV-2) https://www.journalaji.com/index.php/AJI/article/view/30141 <p>Present days world is facing a great challenge to stop a pandemic outbreak of Coronavirus disease 2019 (COVID-19) which is caused by SARS-CoV-2. This was first reported in Wuhan, Hubei, China in December 2019, and it spread rapidly across the world, resulting in the World Health Organization announcing a global health emergency on 30 January 2020.&nbsp; Currently, there is no registered treatment or vaccine for the disease. In the absence of a specific treatment for this novel virus, there is an urgent need to find an alternative solution to prevent and control the replication and spread of the virus. In this situation, we should follow some guidelines or suggestions provided by the renowned health sector such as WHO. First, to increase our immunity, we have to take nutrition supplement or foods which contain immunity enhancer vitamins and minerals. Second, to control this pandemic we should practice good personal hygiene. And if we are affected, we should take some medicine as the doctor’s guideline. In this article, we summarize the possible prevention, treatment and control measures of this pandemic.</p> Md. Mahmudul Islam Khan, Lincon Chandra Shill, Nafisa Habib Purba, Moumita Chakma, Vulon Prosad, Ahmedur Rahman Rumel ##submission.copyrightStatement## https://www.journalaji.com/index.php/AJI/article/view/30141 Tue, 27 Oct 2020 00:00:00 +0000