Asian Journal of Immunology <p style="text-align: justify;"><strong>Asian Journal of&nbsp;Immunology</strong>&nbsp;aims to publish&nbsp;high-quality&nbsp;papers (<a href="/index.php/AJI/general-guideline-for-authors">Click here for Types of paper</a>) in all aspects of the immune system in all organisms. This journal facilitates the research and wishes to publish papers as long as they are technically correct, scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer-reviewed, open access INTERNATIONAL journal.</p> <p style="text-align: justify;">&nbsp;</p> Asian Journal of Immunology en-US Asian Journal of Immunology Henoch-Schonlein Purpura Successfully Treated with Oral Steroids: A Case Report <p>A 38-years old male patient, documented case of Irritable Bowel Syndrome (IBS), presented to the clinic with complaints of severe central abdominal pain and severe rash. The day before presenting to the clinic, the patient went to the Emergency Department for the same complaints.</p> <p>According to the patient, the abdominal pain was colicky in nature. There were no associated complaints of nausea, vomiting, or GI bleeding, but did have an upper respiratory tract infection three weeks ago, after which he had started experiencing these symptoms. His infection was treated with oral antibiotics and was soon got resolved. The staff at the ED had investigated the cause, including a CT abdomen with contrast, but the reports had been all clear. He had mildly raised serum creatinine at that time.</p> <p>On clinical examination, the patient had severe tenderness in his abdominal region. The rash was extensive, reddish, raised, and purpuric in nature and had spread all over his lower limbs and hips on both sides. The upper limbs were also involved up to the forearms.</p> <p>All the lab investigations conducted on the patient were normal, including CBC, Creatinine, Serum C3, C4, and the rheumatoid factor. CRP was found to be elevated and positive occult blood was seen in the stool of the patient.</p> <p>The combination of the above medical symptoms and investigations revealed that the patient was suffering from abdominal angina. The symptoms had a classic presentation pattern: positive occult blood in stool, a purpuric rash, abdominal pain, and renal involvement that was preceded by a documented case of upper respiratory tract infection (URTI).</p> <p>Later, the patient was found to have all findings consistent with immune-mediated IgA vasculitis (Henoch Schonlein Purpura) and was then treated accordingly.</p> <p>The above-mentioned case was an interesting presentation: the condition is not often presented to the hospital with such clear manifestations, leading to an absolute diagnosis. The following sections of this case study will explore how the patient was diagnosed, treated, and managed accordingly to save his life.</p> Mohamed Eltaieb Ali Ashraf Alakkad Naglaa Mohamed Hamed ##submission.copyrightStatement## 2021-12-01 2021-12-01 15 19 Overweight and Obesity in Saudi Patients with Schizophrenia Affects Cholesterol Concentration and Some Immune System Cells <p><strong>Introduction: </strong>Schizophrenia (SZ), a prevalent and highly debilitating mental disease, is associated with high rates of overweight and obesity and effects on different systems of the body including the immune system. There are very few studies worldwide on weight measured by the body mass index (BMI) in patients with SZ and its effect on blood parameters, while there are no such studies in Saudi Arabia.</p> <p><strong>Aims: </strong>This study is the first to determine the effects of weight, measured by the BMI, on the differential complete blood count in patients with SZ. Additionally, the serum lipid profile was determined.</p> <p><strong>Methodology: </strong>Blood samples were collected from 45 randomly chosen male inpatients with SZ with an age range of 28-47 years and a mean age of 37 years.</p> <p><strong>Results: </strong>BMI categorization of the patients showed that 6.7% were underweight, 53.3% were healthy, 24.4% were overweight, and 15.6% were obese. Compared with the healthy BMI, significantly lower cholesterol levels and neutrophil counts were found for the overweight BMI group, while significantly higher cholesterol levels and monocyte percents were found for the obese BMI group.</p> <p><strong>Conclusion: </strong>Most subjects had a healthy BMI while overweight and obese subjects showed effects on cholesterol levels and counts of innate immune system cells.</p> Sawsan Hassan Mahassni Razan Ahmed Alyoubi ##submission.copyrightStatement## 2021-11-09 2021-11-09 1 14